La Liga round No. 25 will see a massive relegation six-pointer take place between Granada and Almeria.
Meanwhile, Real Betis and Alaves will also meet in a relegation six-pointer, as both clubs attempt to move away from the bottom of the table.
Osasuna and Cadiz drew 1-1 earlier this season in La Liga. The last four games between these clubs finished with under 2.5 goals.
Cadiz are 18th in the standings and three points off safety in La Liga. The Yellow Submarine are winless in their last six games, losing five times and drawing once.
Osasuna are 11th and plodding along in the league. The team took 10 points from the last six matches. Los Rojillos are coming off of a 1-0 away win over Real Sociedad. They are a low-scoring team, with just 27 goals in 24 matches.
Sevilla posted a 3W-2D-1L record against Valencia in their last six meetings. Valencia won away at Sevilla earlier this season 2-1. One of the trends between these teams has been red cards. The last four matches between the clubs saw the home team receive a red card.
Valencia lost two of their last three La Liga matches. They are coming off a surprise 2-0 loss to Las Palmas away from home. Los Che play well at home and have a record of 7W-2D-2L this term in La Liga.
Sevilla are coming off a fantastic 1-0 home win over Atletico Madrid. It was their second consecutive win. Los Rojiblancos may be turning the corner and moving away from the bottom three. Sevilla won two of their last four away matches.
Granada and Almeria played out a six-goal thriller earlier this season, with the final score being 3-3. Now, the teams will meet in a La Liga six-point relegation match.
Granada are 19th and seven points off safety. A loss to Almeria would likely mean Granda will be relegated. Granada failed to win 20 of their last 21 La Liga games.
Almeria are in similar poor form. The team failed to win their last 27 La Liga games. Almeria are the only team without a win in La Liga this term.
Alaves are on a great run of form against Real Betis in all competitions. The teams met twice already this season in league and cup competition. Alaves posted a 1-1 draw against Betis in La Liga and won 1-0 in the Copa de Espana.
Betis are in good form in La Liga. They are undefeated in 17 of their last 19 games in the division. Los Verdiblancos are up to sixth in the league standings. They took seven points from the last nine on offer.
Alaves took 11 points from their last 18 points on offer. However, Deportivo failed to win either of their last two fixtures. Alaves were outscored 31-24 in their opening 24 La Liga fixtures.