On Boxing Day Arsenal lost 4:0 to Southampton and surely the Gunners will be highly motivated for success in this meeting. However, Southampton are in a rather good form, winning their last 3 league games.
Despite winning 3 consecutive matches, throughout the season Southampton failed to be consistent enough. This can clearly be seen in the team's Win/Draw/Lost pie chart
So from the statistical point, Southampton losing this game will definitely not be a surprising outcome, bearing in mind they lost 4 of their last 5 away games.
Arsenal on the other hand, have been experiencing some problems lately, as they did not manage to win any of their last 3 league games. However, Alexis Sánchez is fit and should be in the starting eleven, which will certainly have a positive impact on Arsenal's performance. Furthermore, the Gunners have an impressive home record this season and despite recent 4:0 defeat to Southampton, they are favorites to win this one.
Arsenal - Southampton football predictions